For very dry and atopic-prone skin, moisture alone may not be enough. A weakened skin barrier can leave skin more prone to dryness, itching and discomfort, calling for care that goes beyond surface hydration. Uriage, the renowned dermatological skincare brand trusted and recommended by healthcare professionals, today introduces the newly reformulated Xémose C8+ range, developed with Triple Barrier Science to help restore the skin’s three interconnected barriers: microbiome, immune and physical.
At its core is the new C8+ biomimetic innovation, which delivers eight biomimetic ceramides to increase both the quantity and diversity of ceramides in the skin, with enhanced action on the physical barrier. Designed for the whole family, from babies and children to adults, Xémose C8+ brings targeted barrier care to very dry and atopic-prone skin, including concerns such as severe dryness, dry patches, flaking and persistent itching.
Eight Ceramides, One Stronger Skin Barrier
Uriage Xémose C8+: Targeting All Three Skin Barriers
Ceramides naturally make up around 50% of the skin’s lipids, forming part of the “cement” that holds skin cells together. They play an important role in keeping the physical barrier intact, helping to limit water loss, protect against external aggressors and support the skin’s natural repair process.
For atopic-prone skin, ceramide deficiency can weaken this structure. With fewer and less diverse ceramides, the barrier becomes more permeable, making it easier for allergens, bacteria and other irritants to penetrate and contribute to dryness, itching and inflammation.
This is where C8+ comes in. Rather than focusing only on moisturising the skin, the innovation features eight biomimetic ceramides designed to mimic the nature and structure of ceramides naturally found in the skin. Each supports a specific function of the physical barrier, helping restore cohesion, suppleness, flexibility, mechanical resistance and permeability control.
“Atopic skin concerns go beyond surface dryness; they can affect sleep, comfort and overall quality of life,” said Sharon Teo, Brand Manager, Uriage Singapore. “With Xémose C8+, our focus was on going beyond temporary comfort to help restore and strengthen the skin barrier. It’s about providing effective dermatological care that brings immediate, clinically proven relief, even for the most fragile skin in the family,” she added.
Beyond its focus on the physical barrier, Xémose C8+ is built on Triple Barrier Science to act across all three of the skin’s barriers. Uriage Thermal Water and two exclusive patents, TLR2-Regul and Chronoxin, help rebalance the microbiome barrier and regulate the immune barrier, while eight biomimetic ceramides, supported by nourishing actives including Shea Butter, help regenerate the physical barrier.
Through this three-barrier action, Xémose C8+ helps repair and soothe from the first application, with clinically demonstrated 48-hour anti-recurrence efficacy.
From Shower to Daily Care

Left to right: Uriage Xémose C8+ Anti-itch Cleansing Oil, Uriage Xémose C8+ Lipid-Replenishing Anti-itch Cream
The refreshed line-up is anchored by two flagship hero products designed to comfort dry, reactive skin starting from the shower:
Uriage Xémose C8+ Anti-itch Cleansing Oil, 500ml (S$55.90): A gentle, soap-free cleansing oil for very dry, atopic-prone skin, including severe dryness and itching. Formulated with Uriage Thermal Water, eight biomimetic ceramides and Shea Butter, its gel-oil texture transforms into a light foam to gently cleanse while replenishing lipids and nourishing the skin, helping relieve itching and skin tightness from the first application.
Uriage Xémose C8+ Lipid-Replenishing Anti-itch Cream, 200ml (S$38.90): A nourishing daily cream formulated with Uriage Thermal Water, eight biomimetic ceramides and 10% Shea Butter to repair and strengthen very dry, atopic-prone skin, including intense dryness, itching and flaking. Its fresh, lightweight texture absorbs quickly without feeling greasy or sticky, leaving skin hydrated and comfortable, with clinically demonstrated 48-hour anti-itch and anti-recurrence efficacy.
Completing the comprehensive range in Singapore are the Uriage Xémose C8+ SOS Anti-Itch Mist, 200ml (S$33.90) for instant, touchless relief on the go, and the Uriage Xémose C8+ Soothing Toner, 250ml, (S$38.90) to calm extreme facial dryness.
The Uriage Xémose C8+ range is available at Watsons and Guardian. From now until 31 December 2026, Guardian will also carry exclusive 50ml sizes of the Xémose C8+ Anti-Itch Cleansing Oil and Xémose C8+ Lipid-Replenishing Anti-Itch Cream, priced at S$14.90 each, with 60% off the second item during the promotional period.
To learn more about the range and other available products, visit uriage.com.